Genome sequences of human cytomegalovirus strain TB40/E variants propagated in fibroblasts and epithelial cells

Abstract The advent of whole genome sequencing has revealed that common laboratory strains of human cytomegalovirus (HCMV) have major genetic deficiencies resulting from serial passage in fibroblasts.In particular, tropism for epithelial and endothelial cells is lost due to mutations disrupting genes UL128, UL130, or UL131A, which encode subunits o

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The Fight against Illegal, Unreported and Unregulated Fishing

The international community have been of aware of IUU fishing for over a decade.As a result, the FAO adopted an International Plan of Action in 2001 which called upon all its members to take actions against these illegal practices.The EC adopted a Regulation to prevent, deter and eliminate IUU fishing on 29 September 2008.It will enter into force o

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